The Role of the Lived Experience Advisory Panel (LEAP) on the Mindset XR3 DTD study

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The LEAP has been instrumental in the pre-trial phase (Nov 2025 - May 2026). Initial qualitative outputs from the LEAP process indicate that standard Virtual Reality (VR) protocols require adaptation for treating people with Difficult-to-Treat Depression (DTD). The panel's early input on the mobile companion app and VR-Mindfulness-Based Intervention (VR-MBI) programme elements has ensured the intervention is sufficiently sensitive for patients who have previously failed to find relief through standard talking therapies.​​​​​​